Senior NGS Data Analyst

BostonGene is redefining cancer patient care and drug development through the integration of omnimodal data and artificial intelligence. Built and validated through an extensive real-world clinical testing network, BostonGene’s foundation model for tumor and immune biology integrates genomic, transcriptomic, and immune data with clinical outcomes to generate biologically grounded, actionable insights. These insights enable biopharma partners to design and de-risk trials, identify novel targets, and optimize therapeutic response prediction across all stages of development while simultaneously improving patient care through clinically integrated innovation.

The role focuses on translating multi-omics data into clinically actionable insights to support therapy selection and biomarker discovery for precision oncology.

Responsibilities:

• Biological interpretation and analysis of multi-omics data with a focus on NGS (RNA-seq, WES) data;

• Lead data analysis for collaborations with leading US cancer centers (e.g., MD Anderson Cancer Center, Massachusetts General Hospital, National Cancer Institute);

• Review analytical results and biological interpretations produced by team members to ensure scientific quality and consistency;

• Investigate molecular mechanisms underlying differential response to therapy and identify novel tumor biomarkers using internal BostonGene analytical tools;

• Analysis of tumor biology in patient samples including somatic and germline variants, RNA expression;

• Support interpretation of molecular findings to inform personalized treatment strategies for cancer patients;

• Identification and interpretation of biomarkers relevant for therapy selection;

• Matching biomarkers to potential treatment options and clinical trials based on clinical guidelines and scientific literature;

• Curation and maintenance of internal knowledge bases supporting biomarker identification and therapy matching;

• Development and maintenance of Standard Operating Procedures (SOPs) for analytical workflows and quality control;

• Participation in external scientific collaborations focused on tumor biology.

Requirements

• PhD in Bioinformatics, Molecular Biology (or other relevant field) OR 4+ years of proven work experience in biotech company (Master's degree in biological sciences or chemistry, or equivalent);

• Strong knowledge of cancer biology and immunology; understanding of clinical oncology guidelines (e.g., NCCN, ASCO, ESMO) is preferred;

• Fluency in English and Russian is mandatory.

• Track record of scientific publications or projects in life sciences;

• Experience with Python for biological data analysis (e.g., Pandas, Numpy) is preferred;

• Highly organized with strong attention to detail;

• Strong ability to present work results clearly and effectively;

• Experience mentoring junior scientists, students, or analysts in research projects is preferred;

We offer:

• Full-time position with a permanent contract and flexible working hours, with hybrid work options.

• Competitive salary and comprehensive healthcare insurance.

• Convenient office location in Yerevan (1-minute walk from the metro) with on-site snacks.

• Relocation package for candidates and their immediate family members, including full documentation and bureaucracy support (bank accounts, residence permits, school contacts, etc.).

• Corporate benefits, including English language lessons and gym membership.

• Dynamic and versatile professional environment with a diverse team of bioinformaticians, biologists, physicians, and software developers committed to improving oncological healthcare.

• Careful, structured, and responsible supervision to support professional growth.